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Autophagy Hijacking in PBMC From COVID-19 Patients Results in Lymphopenia

Autophagy is a homeostatic process responsible for the self-digestion of intracellular components and antimicrobial defense by inducing the degradation of pathogens into autophagolysosomes. Recent findings suggest an involvement of this process in severe acute respiratory syndrome coronavirus 2 (SAR...

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Hoofdauteurs: Cristiana Barbati, Alessandra Ida Celia, Tania Colasanti, Marta Vomero, Mariangela Speziali, Erisa Putro, Giorgia Buoncuore, Flavia Savino, Serena Colafrancesco, Federica Maria Ucci, Claudia Ciancarella, Eugenia Balbinot, Susanna Scarpa, Francesco Natalucci, Greta Pellegrino, Fulvia Ceccarelli, Francesca Romana Spinelli, Claudio Maria Mastroianni, Fabrizio Conti, Cristiano Alessandri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2022-05-01
Reeks:Frontiers in Immunology
Onderwerpen:
autophagy
apoptosis
inflammation
lymphocytes
SARS-CoV-2
COVID-19
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.903498/full
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