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Human otic progenitor cell models of congenital hearing loss reveal potential pathophysiologic mechanisms of Zika virus and cytomegalovirus infections

ABSTRACTCongenital hearing loss is a common chronic condition affecting children in both developed and developing nations. Viruses correlated with congenital hearing loss include human cytomegalovirus (HCMV) and Zika virus (ZIKV), which causes congenital Zika syndrome. The mechanisms by which HCMV a...

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Hoofdauteurs: Alfred T. Harding, Karen Ocwieja, Minjin Jeong, Yichen Zhang, Valerie Leger, Nairuti Jhala, Konstantina M. Stankovic, Lee Gehrke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2024-04-01
Reeks:mBio
Onderwerpen:
human cytomegalovirus
organoid
inner ear
Zika virus
hearing loss
virus infection
Online toegang:https://journals.asm.org/doi/10.1128/mbio.00199-24
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