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Targeted destruction of photosensitive retinal ganglion cells with a saporin conjugate alters the effects of light on mouse circadian rhythms.

Non-image related responses to light, such as the synchronization of circadian rhythms to the day/night cycle, are mediated by classical rod/cone photoreceptors and by a small subset of retinal ganglion cells that are intrinsically photosensitive, expressing the photopigment, melanopsin. This raises...

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Hlavní autoři: Didem Göz, Keith Studholme, Douglas A Lappi, Mark D Rollag, Ignacio Provencio, Lawrence P Morin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2008-09-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0003153
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