ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease

Introduction and aim: Thiopurine-related leukopenia is associated with polymorphisms in the thiopurine methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X type motif 15 (NUDT15) genes. However, those polymorphisms explain only a fraction of thiopurine-related leukopenia. Our aim was...

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Bibliografiske detaljer

Principais autores:	A. Jena, N. Grover, P. Bhatia, M. Singh, D. Lad, K.K. Prasad, H. Singh, U. Dutta, V. Sharma
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2024-01-01
Serier:	Revista de Gastroenterología de México (English Edition)
Fag:	Colitis ulcerosa Enfermedad de Crohn Azatioprina 6-mercaptopurina Enfermedad inflamatoria intestinal
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2255534X23000063
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