Development of an Analytical Assay for Electrochemical Detection and Quantification of Protein-Bound 3-Nitrotyrosine in Biological Samples and Comparison with Classical, Antibody-Based Methods

Reactive oxygen and nitrogen species (RONS) cause oxidative damage, which is associated with endothelial dysfunction and cardiovascular disease, but may also contribute to redox signaling. Therefore, their precise detection is important for the evaluation of disease mechanisms. Here, we compared thr...

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Hauptverfasser:	Ksenija Vujacic-Mirski, Kai Bruns, Sanela Kalinovic, Matthias Oelze, Swenja Kröller-Schön, Sebastian Steven, Milos Mojovic, Bato Korac, Thomas Münzel, Andreas Daiber
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-05-01
Schriftenreihe:	Antioxidants
Schlagworte:	oxidative stress peroxynitrite protein-bound 3-nitrotyrosine HPLC with electrochemical detection mitochondrial superoxide
Online-Zugang:	https://www.mdpi.com/2076-3921/9/5/388
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