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Efficacy and safety of Zolbetuximab plus chemotherapy for advanced CLDN18.2-positive gastric or gastro-oesophageal adenocarcinoma: a meta-analysis of randomized clinical trials

Abstract Background The benefit of adding Zolbetuximab to the treatment in patients with Claudin-18 isoform 2 (CLDN18.2)-positive, human epidermal growth factor receptor 2-negative, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GC/GEJ) is not yet...

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Principais autores: Francisco Cezar Aquino de Moraes, Eric Pasqualotto, Matheus Pedrotti Chavez, Rafael Oliva Morgado Ferreira, Tiago Biachi De Castria, Rommel Mario Rodríguez Burbano
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-02-01
Serier:BMC Cancer
Fag:
Claudin-18 isoform 2
Zolbetuximab
Gastric adenocarcinoma
Adenocarcinoma of the gastro-oesophageal junction
Oesophageal adenocarcinoma
Online adgang:https://doi.org/10.1186/s12885-024-11980-w
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