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HPMA polymers as functional excipients in dermal nanoformulations of imiquimod

A key challenge in topical drug delivery is the inherently low bioavailability of many active compounds within skin tissue. Here, we present the first comprehensive study investigating the impact of biocompatible hydrophilic polymers based on N-(2-hydroxypropyl)methacrylamide (p(HPMA)) on skin barri...

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Autori principali: Eliška Kurfiřtová, Stanislav Chvíla, Nikola Strnádková, Vendula Janoušková, Petr Chytil, Tomáš Etrych, Jarmila Zbytovská
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-06-01
Serie:International Journal of Pharmaceutics: X
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2590156726000046
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