Dual Role of Dietary Curcumin Through Attenuating AFB1-Induced Oxidative Stress and Liver Injury via Modulating Liver Phase-I and Phase-II Enzymes Involved in AFB1 Bioactivation and Detoxification

It is well understood that liver cytochrome p450 enzymes are responsible for AFB1 bioactivation, while phase-II enzymes regulated by the transcription factor nuclear factor-erythroid-2-related factor 2 (Nrf2) are involved in detoxification of AFB1. In this study, we explored the potential of curcumi...

Cijeli opis

Bibliografski detalji

Glavni autori:	Ishfaq Muhammad, He Wang, Xiaoqi Sun, Xinghe Wang, Meiyu Han, Ziyin Lu, Ping Cheng, Muhammad A. Hussain, Xiuying Zhang
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2018-05-01
Serija:	Frontiers in Pharmacology
Teme:	CYP enzymes Nrf2 AFB1 curcumin liver
Online pristup:	https://www.frontiersin.org/article/10.3389/fphar.2018.00554/full
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!