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Regulation of Microglia-Activation-Mediated Neuroinflammation to Ameliorate Ischemia-Reperfusion Injury via the STAT5-NF-κB Pathway in Ischemic Stroke

Inflammatory reaction after ischemia-reperfusion contributes significantly to a worsened prognosis, and microglia activation is the main resource of inflammation in the nervous system. Targeting STAT5 has been shown to be a highly effective anti-inflammatory therapy; however, the mechanism by which...

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Principais autores: Zhijun Pu, Shengnan Xia, Pengfei Shao, Xinyu Bao, Dan Wu, Yun Xu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-08-01
coleção:Brain Sciences
Assuntos:
dauricine
STAT5
NF-κB
inflammation
ischemia-reperfusion injury
Acesso em linha:https://www.mdpi.com/2076-3425/12/9/1153
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