Improving the Therapeutic Potential of Human Granzyme B for Targeted Cancer Therapy

Conventional cancer treatments lack specificity and often cause severe side effects. Targeted therapeutic approaches are therefore preferred, including the use of immunotoxins (ITs) that comprise cell-binding and cell death-inducing components to allow the direct and specific delivery of pro-apoptot...

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Autors principals:	Georg Melmer, Stefan Barth, Nina Berges, Grit Hehmann-Titt, Sonja Schiffer
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2013-01-01
Col·lecció:	Antibodies
Matèries:	immunotherapy immunotoxin human cytolytic fusion protein bio-engineering serpin B9 surface-charge endosomal release
Accés en línia:	http://www.mdpi.com/2073-4468/2/1/19
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