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Mechanisms of liver steatosis in rats with systemic carnitine deficiency due to treatment with trimethylhydraziniumpropionate

Rats with systemic carnitine deficiency induced by treatment with trimethylhydraziniumpropionate (THP) develop liver steatosis. This study aims to investigate the mechanisms leading to steatosis in THP-induced carnitine deficiency. Rats were treated with THP (20 mg/100 g) for 3 or 6 weeks and were s...

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Principais autores: Markus Spaniol, Priska Kaufmann, Konstantin Beier, Jenny Wüthrich, Michael Török, Hubert Scharnagl, Winfried März, Stephan Krähenbühl
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2003-01-01
coleção:Journal of Lipid Research
Assuntos:
mitochondrial β-oxidation
peroxisomal β-oxidation
peroxisomal proliferation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520328303
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