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Verteporfin attenuates NLRP3 inflammasome activation to alleviate gout arthritis flares

Abstract Background Gout arthritis (GA) is an inflammatory disorder characterized by the deposition of monosodium urate (MSU) crystals within synovial joints due to increased urate concentrations in the body. The NLRP3 inflammasome drives a majority of the inflammatory response to MSU crystals; ther...

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Detalles Bibliográficos
Principais autores: Daniel C. Shippy, Tyler K. Ulland
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-07-01
Series:Journal of Inflammation
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Acceso en liña:https://doi.org/10.1186/s12950-025-00455-9
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