Metal accumulation in paired colon cancer and adjacent tissues and its relationship with genotoxic and epigenetic biomarkers

BackgroundEnvironmental exposure to toxic and trace metals has been implicated in colorectal carcinogenesis through oxidative DNA damage and epigenetic dysregulation. However, human evidence linking tissue-level metal accumulation with epigenetic and genotoxic biomarkers remains limited, particularl...

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Ngā kaituhi matua:	Iman Al-Saleh, Ghofran Al-Qudaihi, Reem Al-Rouqi, Nujud Alrushud, Hissah Alnuwaysir, Samar Alhomoud, Alaa Abdul Jabbar, Luai Ashari, Raha Alahmadi, Hussain Alkhdhur, Salah Addin Falah, Hadeel Almanea, Hussah Alhussaini, Anmar Semilan, Rasha Althebaity, Saud Alharbi
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2026-04-01
Rangatū:	Frontiers in Public Health
Ngā marau:	colon cancer comet assay environmental exposure global DNA methylation tissue–blood biomarkers trace metals
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fpubh.2026.1801314/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!