Nitric Oxide Mediation in Hydroxyurea and Nitric Oxide Metabolites’ Inhibition of Erythroid Progenitor Growth

In several systems, hydroxyurea has been shown to trigger nitric oxide (NO) release or activation of NO synthase (NOS). To elucidate this duality in its pharmacological effects, during myelosuppression, we individually examined hydroxyurea’s (NO releasing agent) and NO metabolites’ (stable NO degrad...

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Principais autores:	Tijana Subotički, Olivera Mitrović Ajtić, Dragoslava Djikić, Marijana Kovačić, Juan F. Santibanez, Milica Tošić, Vladan P. Čokić
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-10-01
Serija:	Biomolecules
Teme:	hydroxyurea nitric oxide erythroid colonies nitric oxide synthase nitrite nitrate
Online dostop:	https://www.mdpi.com/2218-273X/11/11/1562
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