Structural modeling and docking analysis of canonical and novel resistance-associated missense mutations in Sudanese Escherichia coli

Abstract Multidrug-resistant Escherichia coli represents a growing public health challenge in low-resource settings, where therapeutic options and routine genomic surveillance remain limited. Here, we present a structural bioinformatics analysis of resistance-associated missense mutations identified...

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Principais autores:	Edison Eukun Sage, Sabah A. E. Ibrahim, Mohd Firdaus-Raih, Samah Omer A. Samhoon, Ahmed Abdelghyoum M. Mohamed, Tarig M. E. Ahmed, Moaaz M. Saadaldin, Omnia H. Suliman, Osama Mohamed, Sofia B. Mohamed, Qurashi M. Ali
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
Colecção:	Scientific Reports
Assuntos:	Escherichia coli Antimicrobial resistance Missense mutations Novel variants Sudanese clinical isolates Molecular docking
Acesso em linha:	https://doi.org/10.1038/s41598-026-39491-7
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