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The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance

α-klotho (KL) is an anti-aging protein and has been shown to exert anti-inflammatory and anti-oxidative effects in the lung and pulmonary diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The current study investigated the direct effect of KL on the bronchial epithel...

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Principais autores: Jaleesa Garth, Molly Easter, Elex Skylar Harris, Juliette Sailland, Lisa Kuenzi, Samuel Chung, John S. Dennis, Nathalie Baumlin, Adegboyega T. Adewale, Steven M. Rowe, Gwendalyn King, Christian Faul, Jarrod W. Barnes, Matthias Salathe, Stefanie Krick
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
coleção:Frontiers in Medicine
Assuntos:
klotho
mucociliary clearance
TGF-β
airway surface liquid volume
calcium activated potassium channels
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmed.2019.00339/full
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