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CRISPR/Cas9-mediated LMP1 knockout inhibits Epstein-Barr virus infection and nasopharyngeal carcinoma cell growth

Abstract Background A strong association between Epstein-Barr virus (EBV) infection and nasopharyngeal carcinoma (NPC) has been widely recognized in recent decades. The aim of the present study was to investigate latent membrane protein 1 (LMP1) regulation of nasopharyngeal carcinoma (NPC) CNE-2 cel...

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Principais autores: Haifeng Huo, Guohua Hu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-10-01
Serier:Infectious Agents and Cancer
Fag:
CRISPR/Cas9
Nasopharyngeal carcinoma
Epstein-Barr virus (EBV)
LMP1
Growth
Online adgang:http://link.springer.com/article/10.1186/s13027-019-0246-5
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