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Lactoferrin-derived peptide PXL01 impacts nerve regeneration after sciatic nerve reconstruction in healthy and diabetic rats

IntroductionAlthough advanced surgical techniques are available, satisfactory functional outcomes after peripheral nerve injuries are uncommon. Hence, immune-modulating factors such as PXL01, a lactoferrin-derived peptide that improves axonal outgrowth in injured human digital nerves, have gained at...

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Principais autores: Derya Burcu Hazer Rosberg, Margit Mahlapuu, Raquel Perez, Lars B. Dahlin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-04-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
PXL01
nerve reconstruction
autograft
nerve regeneration
diabetes
Goto-Kakizaki rat
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2025.1565285/full
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