The Fractalkine‐CX3CR1 Axis Regulates Non‐inflammatory Osteoclastogenesis by Enhancing Precursor Cell Survival

ABSTRACT The chemokine fractalkine (FKN) is produced by various cell types, including osteoblasts and endothelial cells in bone tissue, and signals through a sole receptor, CX3CR1, which is expressed on monocytes/macrophages, including osteoclast precursors (OCPs). However, the direct effects of FKN...

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Главные авторы:	Yoshikazu Kuboi, Yukiko Kuroda, Masayoshi Ohkuro, Sotaro Motoi, Yoshiya Tomimori, Hisataka Yasuda, Nobuyuki Yasuda, Toshio Imai, Koichi Matsuo
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 2022-10-01
Серии:	JBMR Plus
Предметы:	APOPTOSIS CX3CR1 FRACTALKINE OSTEOCLAST PRECURSOR RANKL
Online-ссылка:	https://doi.org/10.1002/jbm4.10680
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