Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction

Abstract Background Heart failure (HF) with preserved ejection fraction (HFpEF) is increasingly prevalent worldwide due to aging and comorbidities. Epicardial adipose tissue (EAT), favored by diabetes and obesity, was shown to contribute to HFpEF pathophysiology and is an emerging therapeutic target...

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Principais autores:	Nassiba Menghoum, Maria Chiara Badii, Martin Leroy, Marie Parra, Clotilde Roy, Sibille Lejeune, David Vancraeynest, Agnes Pasquet, Dulce Brito, Barbara Casadei, Christophe Depoix, Gerasimos Filippatos, Damien Gruson, Frank Edelmann, Vanessa M. Ferreira, Renaud Lhommel, Masliza Mahmod, Stefan Neubauer, Alexandre Persu, Stefan Piechnik, Kristian Hellenkamp, Ignatios Ikonomidis, Bartosz Krakowiak, Burkert Pieske, Elisabeth Pieske-Kraigher, Fausto Pinto, Piotr Ponikowski, Michele Senni, Jean-Noël Trochu, Nancy Van Overstraeten, Rolf Wachter, Bernhard L. Gerber, Jean-Luc Balligand, Christophe Beauloye, Anne-Catherine Pouleur
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-03-01
Series:	Cardiovascular Diabetology
Assuntos:	Epicardial adipose tissue Heart failure with preserved ejection fraction Diabetes Obesity Metabolic syndrome Inflammation
Acceso en liña:	https://doi.org/10.1186/s12933-025-02688-7
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