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Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex

Astrocyte dysfunction may contribute to epileptogenesis and other neurological deficits in Tuberous Sclerosis Complex (TSC). In particular, decreased expression and function of astrocyte glutamate transporters have been implicated in causing elevated extracellular glutamate levels, neuronal death, a...

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Bibliografiske detaljer
Principais autores: Ling-Hui Zeng, Adam W. Bero, Bo Zhang, David M. Holtzman, Michael Wong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2010-03-01
Serier:Neurobiology of Disease
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996109003751
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