Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

Abstract Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS). However, the epigenetic networks underlying the maintenance of oncogenic signaling and therapeutic response remain unclear. Using a series of epigenetics‐ and complex‐focused CRISPR screens, RUVBL1, the...

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Detalhes bibliográficos

Principais autores:	Mingli Li, Lu Yang, Anthony K. N. Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson, Xiaobao Xu, Wen‐Han Chang, Kazuya Miyashita, Priyanka Singh, Leisi Zhang, Maggie Li, Jun Wu, Jinhui Wang, Bryan Chen, Lai N. Chan, Jaewoong Lee, Xu Hannah Zhang, Steven T. Rosen, Markus Müschen, Jun Qi, Jianjun Chen, Kevin Hiom, Alexander J. R. Bishop, Chun‐Wei Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-06-01
coleção:	Advanced Science
Assuntos:	EEF1A1 epigenetic Ewing sarcoma KAT5 MYC RUVBL1
Acesso em linha:	https://doi.org/10.1002/advs.202206584
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