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Transposable element activity captures human pluripotent cell states

Abstract Human pluripotent stem cells (hPSCs) exist in multiple, transcriptionally distinct states and serve as powerful models for studying human development. Despite their significance, the molecular determinants and pathways governing these pluripotent states remain incompletely understood. Here,...

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Hlavní autoři: Florencia Levin-Ferreyra, Srikanth Kodali, Yingzhi Cui, Alison R S Pashos, Patrizia Pessina, Justin Brumbaugh, Bruno Di Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Nature 2024-12-01
Edice:EMBO Reports
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On-line přístup:https://doi.org/10.1038/s44319-024-00343-y
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