A Potential Lead for Insect Growth Regulator: Design, Synthesis, and Biological Activity Evaluation of Novel Hexacyclic Pyrazolamide Derivatives

Ecdysone receptor (EcR) and chitinase play a critical role in the molting stage of insect pests. Each of them is considered a promising target for the development of novel insect growth regulators (IGRs). In the present paper, a total of 24 (23 novel) hexacyclic pyrazolamide derivatives were designe...

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Principais autores:	Bingbo Guo, Biaobiao Jiang, Chunying Wang, Xiaoyu Jin, Liuyang Wang, Zhaokai Yang, Shihui Luo, Qing Yang, Li Zhang, Xinling Yang
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-04-01
Series:	Molecules
Assuntos:	insect growth regulators pyrazolamide ecdysone receptor chitinase molecular docking dual-target IGRs
Acceso en liña:	https://www.mdpi.com/1420-3049/28/9/3741
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