Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla

The ω6 and ω3 pathways are two major pathways in the biosynthesis of PUFAs. In both of these, delta 6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid or α-linolenic acid. Microbial species have different propensity for accumulating ω6- or ω3-series PUFAs, which may be dete...

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Detalhes bibliográficos

Principais autores:	Haisu Shi (史海粟), Haiqin Chen (陈海琴), Zhennan Gu (顾震南), Yuanda Song (宋元达), Hao Zhang (张灏), Wei Chen (陈卫), Yong Q. Chen (陈永泉)
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2015-12-01
Colecção:	Journal of Lipid Research
Assuntos:	polyunsaturated fatty acids linoleic acid α-linolenic acid arachidonic acid eicosapentaenoic acid chimera
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520309500
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