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Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation

Aging is a major risk factor for cognitive impairment. Aerobic exercise benefits brain function and may promote cognitive health in older adults. However, underlying biological mechanisms across cerebral gray and white matter are poorly understood. Selective vulnerability of the white matter to smal...

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Principais autores: Paul Shin, Qi Pian, Hidehiro Ishikawa, Gen Hamanaka, Emiri T Mandeville, Shuzhen Guo, Buyin Fu, Mohammed Alfadhel, Srinivasa Rao Allu, Ikbal Şencan-Eğilmez, Baoqiang Li, Chongzhao Ran, Sergei A Vinogradov, Cenk Ayata, Eng Lo, Ken Arai, Anna Devor, Sava Sakadžić
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2023-07-01
coleção:eLife
Assuntos:
aging
exercise
cerebral microcirculation
cerebral oxygenation
white matter
two-photon microscopy
Acesso em linha:https://elifesciences.org/articles/86329
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