Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk

Abstract Genome-wide association studies have identified numerous variants associated with human complex traits, most of which reside in the non-coding regions, but biological mechanisms remain unclear. However, assigning function to the non-coding elements is still challenging. Here we apply Activi...

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Bibliografiske detaljer

Principais autores:	Pingting Ying, Can Chen, Zequn Lu, Shuoni Chen, Ming Zhang, Yimin Cai, Fuwei Zhang, Jinyu Huang, Linyun Fan, Caibo Ning, Yanmin Li, Wenzhuo Wang, Hui Geng, Yizhuo Liu, Wen Tian, Zhiyong Yang, Jiuyang Liu, Chaoqun Huang, Xiaojun Yang, Bin Xu, Heng Li, Xu Zhu, Ni Li, Bin Li, Yongchang Wei, Ying Zhu, Jianbo Tian, Xiaoping Miao
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-09-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-023-41690-z
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