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Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles

Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells. We have developed a drug, saposin C-dioleoylphosphatidylserine (SapC-DOPS), that selecti...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Harold W. Davis, Subrahmanya D. Vallabhapurapu, Zhengtao Chu, Michael A. Wyder, Kenneth D. Greis, Venette Fannin, Ying Sun, Pankaj B. Desai, Koon Y. Pak, Brian D. Gray, Xiaoyang Qi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-08-01
Seri Bilgileri:Cells
Konular:
SapC-DOPS nanovesicles
radiation therapy
brain tumor
glioblastoma multiforme
iodination
phosphatidylserine
Online Erişim:https://www.mdpi.com/2073-4409/9/9/1960
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