Minimal Residual Disease Detected by the 7NB-mRNAs ddPCR Assay Is Associated with Disease Progression in High-Risk Neuroblastoma Patients: A Prospective Multicenter Observational Study in Japan

High-risk neuroblastoma (HR-NB) patients remain far from obtaining optimal outcomes, with more than 50% relapse/regrowth rate despite current intensive multimodal therapy. This originated from the activation/proliferation of chemoresistant minimal residual disease (MRD). MRD with a significant progn...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Noriyuki Nishimura, Toshiaki Ishida, Isao Yokota, Kimikazu Matsumoto, Hiroyuki Shichino, Hiroyuki Fujisaki, Takeo Sarashina, Takehiko Kamijo, Tetsuya Takimoto, Tomoko Iehara, Tatsuro Tajiri, on behalf of the JCCG Neuroblastoma Committee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2023-10-01
Цуврал:	Biology
Нөхцлүүд:	neuroblastoma (NB) minimal residual disease (MRD) bone marrow (BM) peripheral blood (PB) neuroblastoma-associated mRNAs (NB-mRNAs) droplet digital PCR (ddPCR)
Онлайн хандалт:	https://www.mdpi.com/2079-7737/12/10/1350
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