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Development of an improved reverse genetics system for avian metapneumovirus (aMPV): A novel vaccine vector protects against aMPV and infectious bursal disease virus

Avian metapneumovirus (aMPV), a paramyxovirus, causes acute respiratory diseases in turkeys and swollen head syndrome in chickens. This study established a reverse genetics system for aMPV subtype B LN16-A strain based on T7 RNA polymerase. Full-length cDNA of the LN16-A strain was constructed by as...

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Principais autores: Lingzhai Meng, Yuntong Chen, Mengmeng Yu, Peng Liu, Xiaole Qi, Xiaoxiao Xue, Ru Guo, Tao Zhang, Mingxue Hu, Wenrui Fan, Ying Wang, Suyan Wang, Yanping Zhang, Yongzhen Liu, Yulu Duan, Hongyu Cui, Yulong Gao
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2025-05-01
coleção:Journal of Integrative Agriculture
Assuntos:
avian metapneumovirus
reverse genetics system
insertion site
protection
vector vaccines
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2095311924001825
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