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In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus

Abstract Background Since its inception in 2001, in utero electroporation (IUE) has been widely used by the neuroscience community. IUE is a technique developed to introduce plasmid DNA into embryonic mouse brains without permanently removing the embryos from the uterus. Given that IUE labels cells...

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Principais autores: Jessica M. Rosin, Deborah M. Kurrasch
格式: Artigo
语言:Inglês
出版: BMC 2018-06-01
丛编:Journal of Neuroinflammation
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在线阅读:http://link.springer.com/article/10.1186/s12974-018-1213-6
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