GLH/VASA helicases promote germ granule formation to ensure the fidelity of piRNA-mediated transcriptome surveillance

Phase separated, membrane-less germ granules preserve fertility and cellular function in animal germ cells. Here the authors show that loss of germ granules impacts piRNA pathway fidelity in the recognition of self and non-self nucleic acids.

Bibliografski detalji

Glavni autori:	Wenjun Chen, Jordan S. Brown, Tao He, Wei-Sheng Wu, Shikui Tu, Zhiping Weng, Donglei Zhang, Heng-Chi Lee
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2022-09-01
Serija:	Nature Communications
Online pristup:	https://doi.org/10.1038/s41467-022-32880-2
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