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CLL cell-derived soluble factors do not influence the functionality of normal B cells

IntroductionHumoral immunodeficiency is frequently observed in patients affected by chronic lymphocytic leukemia (CLL). The reasons for the compromised B-cell responses are only partly understood. We hypothesized that the normal residual B cells in CLL patients are negatively influenced in their fun...

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Bibliografische Detailangaben
Hauptverfasser: Michelle Maria Elbert, Bettina Budeus, Maria Dampmann, Nele Kahlert, Artur Kibler, Gero Knittel, Hans Christian Reinhardt, Ralf Küppers
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-05-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1794418/full
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