Mechanistic insights into 18β-glycyrrhetinic acid-induced apoptosis in SCC-9 cells revealed by TMT proteomics and network pharmacology

Abstract 18β-Glycyrrhetinic acid (18β-GRA), a major bioactive component of licorice, exhibits recognized biological activities in various tumor models. However, its cellular effects and underlying molecular mechanisms in tongue squamous cell carcinoma (TSCC) are not well characterized. This study ai...

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Hlavní autoři:	Hongli Fan, Daichang Yuan, Yi Nan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-05-01
Edice:	Scientific Reports
Témata:	18β-Glycyrrhetinic acid Tongue squamous cell carcinoma Apoptosis TMT-based proteomics Network pharmacology
On-line přístup:	https://doi.org/10.1038/s41598-026-50655-3
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!