Fine excipient materials in carrier-based dry powder inhalation formulations: The interplay of particle size and concentration effects

The contributions of fine excipient materials to drug dispersibility from carrier-based dry powder inhalation (DPI) formulations are well recognized, although they are not completely understood. To improve the understanding of these contributions, we investigated the influences of the particle size...

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Autori principali:	Mustafa M.A. Elsayed, Iman M. Alfagih, Katrina Brockbank, Fawaz Alheibshy, Alhassan H. Aodah, Raisuddin Ali, Khaled Almansour, Ahmed O. Shalash
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-06-01
Serie:	International Journal of Pharmaceutics: X
Soggetti:	Dry powder inhalation Carrier Fine excipient material Quality-by-design (QbD) Critical material attributes Powder rheology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2590156724000239
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