MDM2 inhibitor APG-115 synergizes with ABT-199 to induce cell apoptosis in chronic lymphocytic leukemia

Although clinical outcomes in chronic lymphocytic leukemia (CLL) have greatly improved with several approved small molecular inhibitors, acquired resistance does occur, leading to disease progression and eventual death. Thus, the effort to explore novel inhibitors and combination therapeutic regimen...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ying Cui, Xiaoya Shao, Haiping Yang, Jingyi Xin, Yuanyuan Liu, Mingxiao Zhang, Chuanyue Sun, Ge Chen, Guomin Shen, Xueqiong Meng, Yixiang Chen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-07-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	chronic lymphocytic leukemia APG-115 apoptosis ABT-199 combination
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1441383/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!