QR Code

Activation of the PI3K/AKT signaling pathway by ARNTL2 enhances cellular glycolysis and sensitizes pancreatic adenocarcinoma to erlotinib

Abstract Background Pancreatic adenocarcinoma (PC) is an aggressive malignancy with limited treatment options. The poor prognosis primarily stems from late-stage diagnosis and when the disease has become therapeutically challenging. There is an urgent need to identify specific biomarkers for cancer...

Full description

Saved in:
Main Authors: Weiyu Ge, Yanling Wang, Ming Quan, Tiebo Mao, Evelyne Y. Bischof, Haiyan Xu, Xiaofei Zhang, Shumin Li, Ming Yue, Jingyu Ma, Haiyan Yang, Lei Wang, Zhengyuan Yu, Liwei Wang, Jiujie Cui
Format: Artigo
Language:Inglês
Published: BMC 2024-03-01
Series:Molecular Cancer
Subjects:
Pancreatic adenocarcinoma
ARNTL2
Prognosis
Erlotinib
Targeted therapy, precision oncology
Online Access:https://doi.org/10.1186/s12943-024-01965-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items