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Frailty predicts the onset and dynamic progression of cardio-renal-metabolic multimorbidity: a multistate modeling analysis from the UK Biobank

Abstract Background Frailty has increasingly been recognized as an important contributor to cardio-renal-metabolic (CRM) diseases. However, most previous studies have focused on isolated outcomes or cross-sectional disease status, lacking a dynamic perspective on disease progression. This study aime...

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Bibliografische Detailangaben
Hauptverfasser: Lulu Liu, Xuhou Ji, Guangzan Yu, Yunlong Wang, Hua He
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-04-01
Schriftenreihe:Diabetology & Metabolic Syndrome
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Online-Zugang:https://doi.org/10.1186/s13098-026-02153-9
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