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A heterotrimeric complex of Toxoplasma proteins promotes parasite survival in interferon gamma-stimulated human cells.

Toxoplasma gondii secretes protein effectors to subvert the human immune system sufficiently to establish a chronic infection. Relative to murine infections, little is known about which parasite effectors disarm human immune responses. Here, we used targeted CRISPR screening to identify secreted pro...

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Збережено в:
Бібліографічні деталі
Автори: Eloise J Lockyer, Francesca Torelli, Simon Butterworth, Ok-Ryul Song, Steven Howell, Anne Weston, Philip East, Moritz Treeck
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2023-07-01
Серія:PLoS Biology
Онлайн доступ:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002202&type=printable
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