Comparison of the mechanisms of estrogen disrupting effects between triphenyl phosphate (TPhP) and tris(1,3-dichloro-2-propyl) phosphate (TDCIPP)

As the typical aryl-organophosphate flame retardants (OPFRs), triphenyl phosphate (TPhP) and tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) were reported to be estrogen disruptors. However, estrogen receptor α (ERα) binding experiments could not explain their biological effects. In this study, their...

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Bibliographic Details

Main Authors:	Xiaoya Ji, Na Li, Mei Ma, Xinyan Li, Kongrui Zhu, Kaifeng Rao, Zijian Wang, Jingfeng Wang, Yanjun Fang
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2022-01-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Triphenyl phosphate (TPhP) Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) Estrogen disrupting effects Estrogen receptor α (ERα) G protein-coupled estrogen receptor (GPER) Estrogen biosynthesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651321011817
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