RPD3 and UME6 are involved in the activation of PDR5 transcription and pleiotropic drug resistance in ρ0 cells of Saccharomyces cerevisiae
Abstract Background In Saccharomyces cerevisiae, the retrograde signalling pathway is activated in ρ0/− cells, which lack mitochondrial DNA. Within this pathway, the activation of the transcription factor Pdr3 induces transcription of the ATP-binding cassette (ABC) transporter gene, PDR5, and causes...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2021-11-01
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| coleção: | BMC Microbiology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12866-021-02373-1 |
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