Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

Abstract The development of osteoarthritis (OA) correlates with the expansion of senescent cells in cartilage, which contributes to an inflammatory microenvironment that accelerates matrix degradation and hampers cartilage generation. To address OA, we synthesized small copper sulfide nanoparticles...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Xianming Wang, Yu Cai, Cuixi Wu, Jiamin Liang, Kangning Tang, Zefeng Lin, Lingling Chen, Yao Lu, Qing Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-08-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Copper sulfide nanoparticles Osteoarthritis Senescent chondrocytes Cartilage repair
Acesso em linha:	https://doi.org/10.1186/s12951-023-02036-5
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!