Epidemiological and genetic profiles of ceftazidime/avibactam-resistant Klebsiella pneumoniae conferred by KPC variants in a tertiary hospital in China

ABSTRACT: Objective: The emergence of Klebsiella pneumoniae carbapenemase variants (KPCVs), conferring resistance to ceftazidime/avibactam (CAZ/AVI), represents a critical clinical challenge. However, investigations into KPCV-producing K. pneumoniae (KPCV-Kp) are confined to sporadic clinical cases...

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Главные авторы:	Min Xu, Xiaofen Mo, Yuchao Zhang, Huinan Xia, Huiqiong Jia, Haishen Kong, Qixia Luo, Yiqi Fu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-12-01
Серии:	Journal of Global Antimicrobial Resistance
Предметы:	K. pneumoniae KPC variants KPCV-Kp CAZ/AVI exposure Ω-loop
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2213716525002164
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