Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum?

Abstract The choice of appropriate physical quantities to characterize the biological effects of ionizing radiation has evolved over time coupled with advances in scientific understanding. The basic hypothesis in radiation dosimetry is that the energy deposited by ionizing radiation initiates all th...

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Detalhes bibliográficos

Principais autores:	Fada Guan, Lawrence Bronk, Matthew Kerr, Yuting Li, Leslie A. Braby, Mary Sobieski, Xiaochun Wang, Xiaodong Zhang, Clifford Stephan, David R. Grosshans, Radhe Mohan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-10-01
coleção:	Scientific Reports
Assuntos:	Proton biological effect Linear energy transfer (LET) Microdosimetric lineal energy spectrum Lung cancer cells
Acesso em linha:	https://doi.org/10.1038/s41598-024-73619-x
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