Integrating transcriptomics, metabolomics, and network pharmacology to investigate multi-target effects of sporoderm-broken spores of Ganoderma lucidum on improving HFD-induced diabetic nephropathy rats

Diabetes mellitus (DM) is a major metabolic disease endangering global health, with diabetic nephropathy (DN) as a primary complication lacking curative therapy. Sporoderm-broken spores of Ganoderma lucidum (GLP), an herbal medicine, has been used for the treatment of metabolic disorders. In this st...

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Detalhes bibliográficos

Principais autores:	Lidan Hu, Lili Yu, Zhongkai Cao, Yue Wang, Caifeng Zhu, Yayu Li, Jiazhen Yin, Zhichao Ma, Xuelin He, Ying Zhang, Wunan Huang, Yuelin Guan, Yue Chen, Xue Li, Xiangjun Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
Colecção:	Journal of Pharmaceutical Analysis
Assuntos:	Diabetic nephropathy Metabolome Network pharmacology Sporoderm-broken spores of Ganoderma lucidum Transcriptome
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2095177924002028
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