Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy

Mitochondrial metabolites and their derivatives have been the focus of recent efforts to develop new anti-inflammatory therapeutics. The widely used therapeutic agents dimethyl fumarate (DMF) and metformin have anti-inflammatory properties and have been shown to target metabolism. The mitochondrial...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Yukun Min, Luke A. J. O’Neill
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2023-12-01
Σειρά:	Frontiers in Drug Discovery
Θέματα:	immunometabolism mitochondrial nucleotide release succinate itaconate fumarate mtDNA
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fddsv.2023.1294454/full
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