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Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl− Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in numerous physiological and pathophysiological processes. We have previously reported a S1P-induced nocifensive response in mice by excitation of sensory neurons via activation of an excitatory chloride current. The underlying mole...

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Hlavní autoři: Yanmei Qi, Norbert Mair, Kai K. Kummer, Michael G. Leitner, María Camprubí-Robles, Michiel Langeslag, Michaela Kress
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-02-01
Edice:Frontiers in Molecular Neuroscience
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On-line přístup:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00033/full
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