Copy Number Alterations Suggest a Functional Switch from Innate Immunity to DNA Repair and Drive Clinical Heterogeneity in Plasma Cell Dyscrasias

Background/Objectives: Multiple myeloma (MM) is a genetically complex hematological neoplasm driven by accumulating genomic events. Despite therapeutic advances, MM remains an incurable disease with a complex molecular picture. Characterizing copy number alterations (CNAs) represents a promising str...

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Autors principals:	Igor Valentim Barreto, Wallax Augusto Silva Ferreira, Guilherme Passos de Morais, Jéssica Sousa Cavalcante, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Leidivan Sousa da Cunha, Anna Karolyna da Costa Machado, Isabelle Magalhães Farias, Beatriz Maria Dias Nogueira, Deivide de Sousa Oliveira, Carolina Koury Nassar Amorim, Rodrigo Monteiro Ribeiro, Ana Paula Lopes Moreira, Kaira Mara Cordeiro de Albuquerque, Mateus de Paula Gomes, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes, Edivaldo Herculano Correa de Oliveira, Daniel Pacheco Bruschi, Caroline Aquino Moreira-Nunes
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-05-01
Col·lecció:	International Journal of Translational Medicine
Matèries:	multiple myeloma aCGH monoclonal gammopathy of undetermined significance smoldering multiple myeloma leukemia plasma cell
Accés en línia:	https://www.mdpi.com/2673-8937/6/2/21
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