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Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines.

Intracellular cytokine staining combined with flow cytometry is one of a number of assays designed to assess T-cell immune responses. It has the specific advantage of enabling the simultaneous assessment of multiple phenotypic, differentiation and functional parameters pertaining to responding T-cel...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Steven G Smith, Kaatje Smits, Simone A Joosten, Krista E van Meijgaarden, Iman Satti, Helen A Fletcher, Nadia Caccamo, Francesco Dieli, Francoise Mascart, Helen McShane, Hazel M Dockrell, Tom H M Ottenhoff, TBVI TB Biomarker Working Group
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0138042
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