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Quantification of bactericidal activity using the PATHFAST TB LAM Ag assay during the first 14 days of pulmonary tuberculosis treatment

BackgroundTuberculosis (TB) remains a global health challenge. Culture-free, rapid, and quantitative biomarkers to monitor treatment response are critical to accelerate development of better TB treatments. The PATHFAST TB LAM Ag assay (PATHFAST-LAM), a desktop chemiluminescent enzyme immunoassay tha...

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Principais autores: Ayumi Akinaga, Andreas H. Diacon, Remous Ocloo, Atsushi Yanagida, Naofumi Yoda, Masanori Kawasaki, Yongge Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-05-01
Colecção:Frontiers in Antibiotics
Assuntos:
tuberculosis
treatment monitoring
lipoarabinomannan
biomarker
bacterial load
immunoassay
Acesso em linha:https://www.frontiersin.org/articles/10.3389/frabi.2025.1574688/full
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